Metabolomics and cardiovascular imaging: a combined approach for cardiovascular ageing

Metabolomics and cardiovascular biomarker discovery.

BACKGROUND Metabolomics, the systematic analysis of low molecular weight biochemical compounds in a biological specimen, has been increasingly applied to biomarker discovery. CONTENT Because no single analytical method can accommodate the chemical diversity of the entire metabolome, various methods such as nuclear magnetic resonance spectroscopy (NMR) and mass spectrometry (MS) have been empl...

Nonlinear dynamics of cardiovascular ageing

The application of methods drawn from nonlinear and stochastic dynamics to the analysis of cardiovascular time series is reviewed, with particular reference to the identification of changes associated with ageing. The natural variability of the heart rate (HRV) is considered in detail, including the respiratory sinus arrhythmia (RSA) corresponding to modulation of the instantaneous cardiac freq...

Cardiovascular responses in ageing: a review.

a benchmarking approach to optimal asset allocation for insurers and pension funds

uncertainty in the financial market will be driven by underlying brownian motions, while the assets are assumed to be general stochastic processes adapted to the filtration of the brownian motions. the goal of this study is to calculate the accumulated wealth in order to optimize the expected terminal value using a suitable utility function. this thesis introduced the lim-wong’s benchmark fun...

Metabolomics in Cardiovascular Disease: Towards Clinical Application

Metabolomics were initially defined as the global analysis of all metabolites present in a sample (metabolomics) and the analysis of metabolic responses to drugs and diseases (metabonomics) [Nicholson et al., 1999, Fiehn 2002, Weckwerth and Morgenthal 2005]. These two definitions have an historical origin, while metabolomics has its foundations in microbial and plant sciences metabonomics origi...